10α-Methoxy-1-methyl-d3-9,10-dihydrolysergol

CAS: 35155-28-3

Ref. TR-M262297

Product Information

• Name: 10α-Methoxy-1-methyl-d3-9,10-dihydrolysergol
• Synonyms: Indolo[4,3-fg]quinoline Ergoline-8-methanol Deriv.-d3, (+)-(5R,10S)-Meluol-d3, 1,6-Dimethyl-8ß-(hydroxymethyl)-10a-methoxyergoline-d3, 1-Methyl-d3-10a-methoxydihydrolysergol, 10-Methoxy-1,6-dimethylergoline-8ß-methanol-d3, 1-Methyl-d3-10a-Methoxy-9,10-dihydrolysergol,, 10a-Methoxy-1-methyl-d3-dihydrolysergol, O10,1-Dimethyllumilysergol-d3, MMDL-d3, (+)-(5R,10S)-Meluol, (8β)-10-Methoxy-1,6-dimethylergoline-8-methanol, 1,6-Dimethyl-10-methoxyergoline-8-beta-methanol, 1,6-Dimethyl-8β-(hydroxymethyl)-10α-methoxyergoline, 1-Methyl-10α-methoxydihydrolysergol, 10-Methoxy-1,6-dimethylergoline-8beta-methanol, 10α-Methoxy-1-methyl-9,10-dihydrolysergol, 10α-Methoxy-1-methyldihydrolysergol, Ergoline-8-beta-methanol, 1,6-dimethyl-10-methoxy-, Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, (8β)-, Indolo[4,3-fg]quinoline, ergoline-8-methanol deriv., Lumilysergol, ¹⁰O,1-dimethyl-, O¹⁰,1-Dimethyllumilysergol, [(8Beta,10Xi)-10-Methoxy-1,6-Dimethylergolin-8-Yl]Methanol, Lumilysergol, 10O,1-dimethyl-

Description

Applications α-Methoxy-1-methyl-d3-9,10-dihydrolysergol is the labeled analogue of 10α-Methoxy-1-methyl-9,10-dihydrolysergol (M262295), a nicergoline (N394550) metabolite that has been shown to have antioxidant activity, preventing glutathione (GSH) depletion and lipid peroxidation; thus it has shown potential as treatment of neuroleptic-induced side effects.
References Vairetti, M., et. al.: Eur. J. Pharmacol., 453, 69 (2002)

• Brand: TRC

Chemical properties

• Molecular weight: 303.41
• Formula: C₁₈H₂₁D₃N₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C18H24N2O2/c1-19-10-13-7-16-18(22-3,8-12(11-21)9-20(16)2)14-5-4-6-15(19)17(13)14/h4-6,10,12,16,21H,7-9,11H2,1-3H3/t12-,16-,18+/m1/s1/i1D3
• InChI key: InChIKey=LVXVIPZBNJSUKL-ZPBJSYQOSA-N
• SMILES: [2H]C([2H])([2H])n1cc2c3c(cccc31)[C@@]1(OC)C[C@@H](CO)CN(C)[C@@H]1C2