[(Methoxy)methyl]triphenylphosphonium Chloride

CAS: 4009-98-7

Ref. TR-M264680

Product Information

• Name: [(Methoxy)methyl]triphenylphosphonium Chloride
• Synonyms: (Methoxymethyl)triphenylphosphonium Chloride, (Methoxymethyl)triphenylphosphonium Chloride, NSC 49223, Triphenyl(methoxymethyl)phosphonium Chloride
• Brand: TRC

Description

Applications [(Methoxy)methyl]triphenylphosphonium Chloride is used in the synthesis of Cephalotaxine (C261050), an antiviral and antitumor agent. Also used in the synthesis of Taxol A fragment.
References Sells, M., et al.: J. Virol., 62, 2836 (1988), Kaneko, S., et al.: J. Clin. Microbiol., 27, 1930 (1989), Baba, Y., et al.: Bioorg. Med. Chem., 13, 5164 (2005), Romero, M., et al.: Antiviral Res., 68, 75 (2005); Hirai, S. et al.: Tetrahedron Lett., 54, 1888 (2013); Xing, P. et al.: Synth., 45, 596 (2013);

Chemical properties

• Molecular weight: 342.8
• Formula: C₂₀H₂₀OP·Cl
• Color/Form: Neat
• InChI: InChI=1S/C20H20OP.ClH/c1-21-17-22(18-11-5-2-6-12-18,19-13-7-3-8-14-19)20-15-9-4-10-16-20;/h2-16H,17H2,1H3;1H/q+1;/p-1
• SMILES: COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Cl-]