3-Methoxy-10H-phenothiazine

CAS: 1771-19-3

Ref. TR-M265405

Product Information

• Name: 3-Methoxy-10H-phenothiazine
• Synonyms: 3-Methoxyphenothiazine, 10H-Phenothiazine, 3-methoxy-, Phenothiazine, 3-methoxy-

Description

Applications 3-Methoxy-10H-phenothiazine is used in the synthesis of 10-Dechlorovancomycin (D226740), which is an impurity of Vancomycin (V096500, HCl salt) which is an amphoteric glycopeptide antibiotic produced by Streptomyces orientalis discovered in soil. Vancomycin inhibits bacterial cell wall synthesis by binding to peptidoglycan.
References Marshall, F.J., et al.: J. Med. Chem., 8, 18 (1965), Cunha, B.A., et al.: Med. Clin. North Am., 79, 817 (1995), Li, L., et al.: Ther. Drug Monit., 17, 366 (1995)

• Brand: TRC

Chemical properties

• Molecular weight: 229.3
• Formula: C₁₃H₁₁NOS
• Color/Form: Neat
• InChI: InChI=1S/C13H11NOS/c1-15-9-6-7-11-13(8-9)16-12-5-3-2-4-10(12)14-11/h2-8,14H,1H3
• InChI key: InChIKey=NKRGJNZQQYCJHD-UHFFFAOYSA-N
• SMILES: COc1ccc2c(c1)Sc1ccccc1N2