5-Methoxytryptamine

CAS: 608-07-1

Ref. TR-M271695

Product Information

• Name: 5-Methoxytryptamine
• Synonyms: 2-(5-Methoxy-1H-indol-3-yl)ethanamine, Melatonin Related Compound A (USP), Melatonin Related Compound A, (5-methoxy-1H-indol-3-yl)acetic acid, 1H-Indole-3-ethanamine, 5-methoxy-, 2-(5-Methoxy-1H-indol-3-yl)ethan-1-amine, 2-(5-Methoxyindol-3-yl)ethylamin, 2-(5-Methoxyindol-3-yl)ethylamine, 2-(5-Methoxyindole-3-Yl)Ethylamine, 2-(5-Metoxiindol-3-Il)Etilamina, 2-(5-methoxy-1H-indol-3-yl)ethanamine, 2-[5-(Methyloxy)-1H-indol-3-yl]ethanamine, 3-(2-Aminoethyl)-5-methoxyindole, 5-22-12-00018, 5-MeOT, 5-Methoxy-1H-indole-3-ethanamine, 5-Mot, 5Mot, Brn 0145587, Deacetylmelatonin, Indole, 3-(2-aminoethyl)-5-methoxy-, Meksamin (free base), Methoxytryptamine, Mexamine, Mexamine base, Nsc 56422, [2-(5-Methoxy-1H-indol-3-yl)ethyl]amine

Description

Impurity Melatonin USP Related Compound A
Applications A tryptamine derivative that is closely related to the neurotransmitter Melatonin (M215000) and Serotonin (S274980). It acts as a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6, and 5-HT7 receptors but has no affinity for the 5-HT3 receptor (1,2,3,4). Melatonin USP Related Compound A.
References (1) Yamada, J. et al.: Eur. J. Pharmacol., 323, 235 (1997)(2) Craig, D.A. et al.: NAun. Schmied. Arch. Pharmacol., 342, 9 (1990) (3) Hemedah, M. et al.: Br. J. Pharmacol., 126, 179 (1999)(4) Millan-Plano, S. et al.: Int. J. Mol. Sci., 11, 312 (2010)

• Brand: TRC

Chemical properties

• Molecular weight: 190.24
• Formula: C₁₁H₁₄N₂O
• Color/Form: Light Brown
• InChI: InChI=1S/C11H14N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3
• InChI key: InChIKey=JTEJPPKMYBDEMY-UHFFFAOYSA-N
• SMILES: COc1ccc2[nH]cc(CCN)c2c1