N-Methyl-L-alanine-13CD3

CAS: 3913-67-5

Ref. TR-M276566

Product Information

• Name: N-Methyl-L-alanine-13CD3
• Synonyms: (S)-2-(Methylamino)propanoic Acid-13CD3, (S)-N-Methylalanine-13CD3, 2-(Methylamino)propanoic Acid-13CD3, N-Methylalanine-13CD3, alpha-(Methylamino)propionic Acid-13CD3, (2S)-2-(Methylamino)propanoic acid, (S)-2-(Methylamino)propanoic acid, (S)-N-Methylalanine, 2-(Methylamino)propanoic acid, <span class="text-smallcaps">L</span>-Alanine, N-methyl-, Alanine, N-methyl-, <span class="text-smallcaps">L</span>-, N-Me-Ala-OH, N-Methyl-<span class="text-smallcaps">L</span>-alanine, N-Methyl-L-Aminopropanoic Acid, N-Methylalanine, N-α-Methyl-L-alanine, α-(Methylamino)propionic acid, Alanine, N-methyl-, L-, N-Methyl-L-alanine, L-Alanine, N-methyl-

Description

Applications N-Methyl-L-alanine-13CD3 is an intermediate used in the synthesis of Mertansine-13CD3 (M257802), which is the isotope labelled analog of Mertansine (M257800); a cytotoxic agent used as the cytotoxic component in antibody-drug conjugates.
References Erickson, H., et al.: Cancer Res., 66, 4426 (2006); Kellogg, B., et al.: Bioconjugate Chem., 22, 717 (2011)

• Brand: TRC

Chemical properties

• Molecular weight: 107.131
• Formula: CC₃D₃H₆NO₂
• Color/Form: Neat
• InChI: InChI=1S/C4H9NO2/c1-3(5-2)4(6)7/h3,5H,1-2H3,(H,6,7)/t3-/m0/s1/i2+1D3
• InChI key: InChIKey=GDFAOVXKHJXLEI-NEKAAMMESA-N
• SMILES: [2H][13C]([2H])([2H])N[C@@H](C)C(=O)O