N’-(1-Methylazepan-4-yl)benzohydrazine Monohydrochloride Salt

CAS: 117078-69-0

Ref. TR-M288685

Product Information

• Name: N’-(1-Methylazepan-4-yl)benzohydrazine Monohydrochloride Salt
• Synonyms: Benzoic acid, 2-(hexahydro-1-methyl-1H-azepin-4-yl)hydrazide, hydrochloride (1:1), Benzoic acid, 2-(hexahydro-1-methyl-1H-azepin-4-yl)hydrazide, monohydrochloride (9CI)
• Brand: TRC

Description

Impurity Azelastine EP Impurity B/Azelastine USP Related Compound B
Stability Hygroscopic
Applications An intermediate in the preparation of Azelastine (A808250(P)), which is an orally active H1-hystamine receptor antagonist and an antihistaminic.
References Scheffler, G. et al.: Arch. Pharm., 321, 205 (1988); Tasaka, K., et al.: Arzneim.-Forsch., 29, 488 (1979); Chand, N., et al.: Int. J. Immunopharmacol., 7, 833 (1985)

Chemical properties

• Molecular weight: 283.8
• Formula: C₁₄H₂₁N₃O·ClH
• Color/Form: Neat
• InChI: InChI=1S/C14H21N3O.ClH/c1-17-10-5-8-13(9-11-17)15-16-14(18)12-6-3-2-4-7-12;/h2-4,6-7,13,15H,5,8-11H2,1H3,(H,16,18);1H
• InChI key: InChIKey=LBMOWZCEDIZQOM-UHFFFAOYSA-N
• SMILES: CN1CCCC(NNC(=O)c2ccccc2)CC1.Cl