Methyl Benzilate

CAS: 76-89-1

Ref. TR-M289750

Product Information

• Name: Methyl Benzilate
• Synonyms: Benzilic Acid Methyl Ester, 2-Hydroxy-2,2-diphenylacetic Acid Methyl Ester, Methyl 2-Hydroxy-2,2-diphenylacetate, Methyl Diphenylglycolate, Methyl Hydroxydiphenylacetate, Methyl a-Hydroxydiphenylacetate, Methyl a-Phenylmandelate, NSC 57672, NSC 624, 2-Hydroxy-2,2-diphenylacetic acid methyl ester, Benzeneacetic acid, .alpha.-hydroxy-.alpha.-phenyl-, methyl ester, Benzeneacetic acid, α-hydroxy-α-phenyl-, methyl ester, Benzilic acid, methyl ester, Benzilic acid, methyl ester (8CI), Methyl 2-hydroxy-2,2-diphenylacetate, Methyl diphenylglycolate, Methyl hydroxy(diphenyl)acetate, Methyl hydroxydiphenylacetate, Methyl α-hydroxydiphenylacetate, Methyl α-phenylmandelate, Methyl benzilate

Description

Applications Methyl Benzilate is a reactant in the synthesis of Trimethadione (T796155), an anticonvulsant and antiepileptic agent used in the treatment of pregnant women. Prenatal exposure to snti-epileptic drugs (AEDs) has indicated increased risk of major or minor congenital malformation.
References Pastore, V., et. al.: Bioorg. Med. Chem., 21, 841 (2013); Ahir, B. et al.: Toxicol. Vitro., 28, 948 (2014); Pastore, V. et al.: Bioorg. Med. Chem., 21, 841 (2013)

• Brand: TRC

Chemical properties

• Molecular weight: 242.27
• Formula: C₁₅H₁₄O₃
• Color/Form: Off White Powder
• InChI: InChI=1S/C15H14O3/c1-18-14(16)15(17,12-8-4-2-5-9-12)13-10-6-3-7-11-13/h2-11,17H,1H3
• InChI key: InChIKey=CXEDBYAXQXFDHD-XNZWOTSQSA-N
• SMILES: N[C@@H](CCC(=O)N[C@@H](CSC1CCOP(=O)(N(CCCl)CCCl)N1)C(=O)NCC(=O)O)C(=O)O