Methyl 8-Chloro-8-oxooctanoate

CAS: 41624-92-4

Ref. TR-M295295

Product Information

• Name: Methyl 8-Chloro-8-oxooctanoate
• Synonyms: 7-(Chloroformyl)heptanoic Acid Methyl Ester, 7-(Methoxycarbonyl)heptanoyl Chloride, 7-Carbomethoxyheptanoyl Chloride, 8-Chloro-8-oxooctanoic Acid Methyl Ester, Methyl 7-(Chlorocarbonyl)heptanoate, Methyl 7-(Chloroformyl)heptanoate, Suberic Chloride Methyl Ester, Suberoyl Chloride Monomethyl Ester

Description

Applications Methyl 8-Chloro-8-oxooctanoate is used as a reagent in the synthesis of β-cyclodextrin-6-deoxy-6-NHC(O)(CH2)6C(O)NHOH which is a β-cyclodextrin-capped histone deacetylase inhibitor that may have potential for use in treatment of cancers and inflammatory diseases. It is also used in one synthetic route for tubacin which is a known anticancer agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Amin, J., et al.: Bioorg. Med. Chem. Lett., 23, 3346 (2013); Hong, J., et al.: Lett. Org. Chem., 7, 50 (2010);

• Brand: TRC

Chemical properties

• Molecular weight: 206.67
• Formula: C₉H₁₅ClO₃
• Color/Form: Neat
• InChI: InChI=1S/C9H15ClO3/c1-13-9(12)7-5-3-2-4-6-8(10)11/h2-7H2,1H3
• InChI key: InChIKey=RKUPOLBFJIEWBZ-UHFFFAOYSA-N
• SMILES: COC(=O)CCCCCCC(=O)Cl