N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

CAS: 477600-74-1

Ref. TR-M296155

Product Information

• Name: N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• Synonyms: (3R,4R)-Methyl{(4-methylpiperidin-3-yl)(7H-pyrrolo[2,3-d]pyrimidin-4-yl)}amine, N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-1H-Pyrrolo[2,3-d]pyrimidin-4-amine
• Brand: TRC
• Description: Applications N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a substance used in the identification of related substances in the degradation products of tofacitinib citrate using LC-MS technique for process monitoring and quality assurance. A reagent for the synthesis of Tofacitinib (CP-690,550), a Janus tyrosine kinase (JAK3) specific inhibitor.References Wu, X., et al.: J. Pharm. Biomed. Anal., 143, 17 (2017); Marican, A., et al.: Tetrahedron Lett., 54, 5096 (2013)

Chemical properties

• Molecular weight: 245.32
• Formula: C₁₃H₁₉N₅
• Color/Form: White
• InChI: InChI=1S/C13H19N5/c1-9-3-5-14-7-11(9)18(2)13-10-4-6-15-12(10)16-8-17-13/h4,6,8-9,11,14H,3,5,7H2,1-2H3,(H,15,16,17)/t9-,11+/m1/s1
• InChI key: InChIKey=XRIARWQZLGCQDM-KOLCDFICSA-N
• SMILES: C[C@@H]1CCNC[C@@H]1N(C)c1ncnc2[nH]ccc12