Methyl 2,4-Dihydroxy-6-methylbenzoate

CAS: 3187-58-4

Ref. TR-M302230

Product Information

• Name: Methyl 2,4-Dihydroxy-6-methylbenzoate
• Synonyms: 6-Methyl-β-resorcylic Acid Methyl Ester, 2,4-Dihydroxy-6-methylbenzoic Acid Methyl Ester, Methyl 2,4-Hydroxy-6-methylbenzoate, Methyl 6-Methyl-β-resorcylate, Methyl o-Orsellinate, Methyl Orsellinate, Orsellinic Acid Methyl Ester, Orsellinic Acid Monomethyl Ester
• Brand: TRC
• Description: Applications Methyl 2,4-Dihydroxy-6-methylbenzoate is a useful synthetic intermediate in the synthesis of Grifolic Acid (G786500); a selective partial GPR120 agonist. Grifolic Acid induces ERK and [Ca2+]i responses in cells expressing GPR120, but has no effects on those expressing GPR40.References Hara, T. et al.: Naun. Schmied. Arch. Pharmacol., 380, 247 (2009); Sun. Q. et al.: Mol. Pharmacol., 78, 804 (2010)

Chemical properties

• Molecular weight: 182.17
• Formula: C₉H₁₀O₄
• Color/Form: Neat
• InChI: InChI=1S/C9H10O4/c1-5-3-6(10)4-7(11)8(5)9(12)13-2/h3-4,10-11H,1-2H3
• InChI key: InChIKey=NCCWCZLEACWJIN-UHFFFAOYSA-N
• SMILES: COC(=O)c1c(C)cc(O)cc1O