N-Methyl Esomeprazole-d3(Mixture of isomers with the methylated nitrogens of imidazole)

CAS: 1346240-11-6

Ref. TR-M304642

Product Information

• Name: N-Methyl Esomeprazole-d3(Mixture of isomers with the methylated nitrogens of imidazole)
• Synonyms: (S)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1-methyl-1H-benzo[d]imidazole-d3 and (S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1-methyl-1H-benzo[d]imidazole-d3 (1:1)

Description

Applications N-Methyl Esomeprazole-d3 is the isotope labelled analog of N-Methyl Esomeprazole (M304640); an impurity of Omeprazole (O635000) which a compound that binds covalently to proton pumps and inhibits gastric secretion. Also used as an antiulcerative.
References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)

• Brand: TRC

Chemical properties

• Molecular weight: 362.46
• Formula: C₁₈H₁₈D₃N₃O₃S
• Color/Form: Neat
• InChI: InChI=1S/2C18H21N3O3S/c1-11-9-19-15(12(2)17(11)24-5)10-25(22)18-20-14-8-13(23-4)6-7-16(14)21(18)3;1-11-9-19-15(12(2)17(11)24-5)10-25(22)18-20-14-7-6-13(23-4)8-16(14)21(18)3/h2*6-9H,10H2,1-5H3/t2*25-/m00/s1/i2*3D3
• InChI key: InChIKey=GLKMBUOPNWZBCK-IPPKCVMMSA-N
• SMILES: [2H]C([2H])([2H])n1c([S@@](=O)Cc2ncc(C)c(OC)c2C)nc2cc(OC)ccc21.[2H]C([2H])([2H])n1c([S@@](=O)Cc2ncc(C)c(OC)c2C)nc2ccc(OC)cc21