Methyl 2-Iodobenzoate

CAS: 610-97-9

Ref. TR-M313675

Product Information

• Name: Methyl 2-Iodobenzoate
• Synonyms: 2-Iodobenzoic Acid Methyl Ester, o-Iodobenzoic Acid Methyl Ester, Methyl o-Iodobenzoate, NSC 34638, 2-Iodo Methyl Benzoate, Benzoic acid, 2-iodo-, methyl ester, Benzoic acid, o-iodo-, methyl ester, Methyl o-iodobenzoate, Methyl 2-iodobenzoate

Description

Stability Light Sensitive
Applications Methyl 2-Iodobenzoate is used as a reagent in the synthesis of Montelukast Sodium Salt (M568000); a selective leukotriene D4-receptor antagonist that is used as an antiasthmatic. Methyl 2-Iodobenzoate is also used as a reagent in the synthesis of isoquinolinone-based tricycles as polyribose polymerase-1 inhibitors.
References Bollikonda, S., et al.: J. Org. Chem., 80, 3891 (2015); Labelle, M., et al.: Bioorg. Med. Chem. Lett., 5, 283 (1995); Jones, T.R., et al.: Can. J. Physiol. Pharmacol., 73, 191 (1995); Markham, A. and Faulds, D.: Drugs, 56, 251 (1998); Chen, J., et al.: Bioorg. Med. Chem. Lett., 24, 2669 (2014)

• Brand: TRC

Chemical properties

• Molecular weight: 262.04
• Formula: C₈H₇IO₂
• Color/Form: Colourless To Light Yellow
• InChI: InChI=1S/C8H7IO2/c1-11-8(10)6-4-2-3-5-7(6)9/h2-5H,1H3
• InChI key: InChIKey=BXXLTVBTDZXPTN-UHFFFAOYSA-N
• SMILES: COC(=O)c1ccccc1I