N-Methyl Lacosamide

CAS: 2764892-65-9

Ref. TR-M315210

Product Information

• Name: N-Methyl Lacosamide
• Synonyms: (R)-2-(Acetylamino)-3-methoxy-N-methyl-N-(phenylmethyl)-propanamide, (R)-2-Acetamido-N-benzyl-3-methoxy-N-methylpropanamide

Description

Applications N-Methyl Lacosamide is the methly analogue of Lacosamide (L098500), a medication used for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. Lacosamide is a potent anticonvulsant.
References Lees, G., et al.: Brain Res., 612, 190 (1993), Kuo, C., et al.: Mol. Pharmacol., 51, 1077 (1997); Barton, M., et al.: Epilepsy Res., 47, 217 (2001); Beyreuther, B., et al.: Eur. J. Pharmacol., 539, 64 (2006); Beyreuther, B., et al.: CNS Drug Rev., 13, 21 (2007)

• Brand: TRC

Chemical properties

• Molecular weight: 264.32
• Formula: C₁₄H₂₀N₂O₃
• Color/Form: Colourless To Yellow
• InChI: InChI=1S/C14H20N2O3/c1-11(17)15-13(10-19-3)14(18)16(2)9-12-7-5-4-6-8-12/h4-8,13H,9-10H2,1-3H3,(H,15,17)/t13-/m1/s1
• InChI key: InChIKey=SGYKCQVUCNHDRI-CYBMUJFWSA-N
• SMILES: COC[C@@H](NC(C)=O)C(=O)N(C)Cc1ccccc1