5-(1-Methyl-4-piperidinyl)-5H-dibenzo[a,d]cyclohepten-5-ol

CAS: 3967-32-6

Ref. TR-M321260

Product Information

• Name: 5-(1-Methyl-4-piperidinyl)-5H-dibenzo[a,d]cyclohepten-5-ol
• Synonyms: 5-(1-Methylpiperidin-4-yl)-5H-dibenzo[a,d][7]annulen-5-ol, 5-(1-Methyl-4-piperidyl)-5H-dibenzo[a,d]cyclohepten-5-ol, 5-(1-Methylpiperidin-4-yl)-5H-dibenzo[a,d]cyclohepten-5-ol, 5H-Dibenzo[a,d]cyclohepten-5-ol, 5-(1-methyl-4-piperidyl)-, 5H-dibenzo[a,d]cyclohepten-5-ol, 5-(1-methyl-4-piperidinyl)-

Description

Applications 5-(1-Methyl-4-piperidinyl)-5H-dibenzo[a,d]cyclohepten-5-ol is a derivative of Cyproheptadine (C989200) which is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. Cyproheptadine is a 5-HT2/5-HT1C serotonin receptor antagonist; H1 histamine receptor antagonist; antipruritic.
References Marchei, E., et al.: J. Pharm. Biomed. Anal., 41, 1633 (2006); de-Benedictis, F., et al.: Allergy, 63, 1395 (2008); Feas, X., et al.: J. Pharm. Biomed. Anal., 50, 1044 (2009); Yu, C., et al.: Talanta, 2011, 83, 1376 (2011);

• Brand: TRC

Chemical properties

• Molecular weight: 305.41
• Formula: C₂₁H₂₃NO
• Color/Form: Neat
• InChI: InChI=1S/C21H23NO/c1-22-14-12-18(13-15-22)21(23)19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-11,18,23H,12-15H2,1H3
• InChI key: InChIKey=NPSCPXDYXVEYQW-UHFFFAOYSA-N
• SMILES: CN1CCC(C2(O)c3ccccc3C=Cc3ccccc32)CC1