D-threo-Methylphenidate Hydrochloride

CAS: 19262-68-1

Ref. TR-M325675

Product Information

• Name: D-threo-Methylphenidate Hydrochloride
• Synonyms: (aR,2R)-a-Phenyl-2-piperidineacetic acid methyl ester hydrochloride (1:1), 2-Piperidineacetic acid, a-phenyl-, methyl ester, hydrochloride, (aR,2R)- (9CI), 2-Piperidineacetic acid, a-phenyl-, methyl ester, hydrochloride, (aR,2R)-(+)- (8CI), 2-Piperidineacetic acid, a-phenyl-, methyl ester, hydrochloride, [R-(R*,R*)]-, Dexmethylphenidate hydrochloride, Focalin, (2R,2'R)-(+)-threo-Methyl a-Phenyl-a-(2-piperidyl)acetate Hydrochloride, 2-Piperidineacetic acid, α-phenyl-, methyl ester, hydrochloride (1:1), (αR,2R)-, 2-Piperidineacetic acid, α-phenyl-, methyl ester, hydrochloride, (αR,2R)-, 2-Piperidineacetic acid, α-phenyl-, methyl ester, hydrochloride, [R-(R*,R*)]-, <span class="text-smallcaps">D</span>-threo-Methylphenidate hydrochloride, D-Methylphenidate, Dexmethylphenidate Hydrochloride, methyl (2R)-phenyl[(2R)-piperidin-2-yl]ethanoate, methyl (2R)-phenyl[(2R)-piperidin-2-yl]ethanoate Hydrochloride (1:1), d-threo-Methylphenidate hydrochloride

Description

Applications Controlled substance. CNS stimulant. The more potent isomers of Methylphenidate. The threo enantomers have shown that the pharmacological activity residues predominantly in the d-threo enantiomer.
References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961), Padmanabhan, G.R., et al.: Anal. Profiles Drug Subs., 10, 473 (1981), Kuczenski, R., et al.: J. Pharmacol. Exp. Ther., 296, 876 (2001), Pelham, W.E., et al.: J. Consult. Clin. Psychol., 61, 506 (1993), Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993),

• Brand: TRC

Chemical properties

• Molecular weight: 269.77
• Formula: C₁₄H₁₉NO₂·ClH
• Color/Form: White To Off-White
• InChI: InChI=1S/C14H19NO2.ClH/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12;/h2-4,7-8,12-13,15H,5-6,9-10H2,1H3;1H/t12-,13-;/m1./s1
• InChI key: InChIKey=JUMYIBMBTDDLNG-OJERSXHUSA-N
• SMILES: COC(=O)[C@H](c1ccccc1)[C@H]1CCCCN1.Cl