2-​[(RS)​-​(4-​Methylphenyl)​phenylmethoxy]​-​N,​N-​dimethylethanamine Hydrochloride

CAS: 4024-34-4

Ref. TR-M325788

Product Information

• Name: 2-​[(RS)​-​(4-​Methylphenyl)​phenylmethoxy]​-​N,​N-​dimethylethanamine Hydrochloride
• Synonyms: Dimenhydrinate Imp. G (EP), Diphenhydramine Hydrochloride Imp. B (EP), Diphenhydramine Imp. B (EP), Orphenadrine USP Related Compound F, Orphenadrine USP RC F, 4-Methyldiphenhydramine Hydrochloride, (RS)-N,N-Dimethyl-2-[(4-methylphenyl)phenylmethoxy]ethanamine Hydrochloride, N,N-Dimethyl-2-[(RS)-(4-methylphenyl)(phenyl)methoxy]ethanamine Hydrochloride, Orphenadrine Hydrochloride Imp. F (EP) as Hydrochloride, para-Methylbenzyl Isomer Hydrochloride of Orphenadrine, Dimenhydrinate Imp. G (EP) as Hydrochloride, Diphenhydramine Hydrochloride Imp. B (EP) as Hydrochloride, Orphenadrine Related Compound F as Hydrochloride, Dimenhydrinate Impurity G as Hydrochloride, Diphenhydramine Hydrochloride Impurity B as Hydrochloride, Orphenadrine Hydrochloride Impurity F as Hydrochloride, Diphenhydramine Impurity B as Hydrochloride, Orphenadrine Impurity F as Hydrochloride, 2-((p-Methyl-alpha-phenylbenzyl)oxy)ethyl(dimethyl)ammonium chloride, 4-Methyldiphenhydramine hydrochloride, Ethanamine, N,N-dimethyl-2-[(4-methylphenyl)phenyl methoxy]-, hydrochloride, Ethanamine, N,N-dimethyl-2-[(4-methylphenyl)phenylmethoxy]-, hydrochloride (1:1), Ethylamine, N,N-dimethyl-2-((p-methyl-alpha-phenylbenzyl)oxy)-, hydrochloride, Ethylamine, N,N-dimethyl-2-(alpha-(p-tolyl)benzyloxy)-, hydrochloride, Ethylamine, N,N-dimethyl-2-[(p-methyl-α-phenylbenzyl)oxy]-, hydrochloride, N,N-Dimethyl-2-((p-methyl-alpha-phenylbenzyl)oxy)ethylamine hydrochloride, N,N-Dimethyl-2-(alpha-(p-tolyl)benzyloxy)ethylamine hydrochloride, N,N-dimethyl-2-[(4-methylphenyl)(phenyl)methoxy]ethanaminium chloride, Neo-benodine, Neobenodine, Toladryl, Toladryl hydrochloride

Description

Impurity Diphenhydramine Impurity B Hydrochloride
Applications 2-​[(RS)​-​(4-​Methylphenyl)​phenylmethoxy]​-​N,​N-​dimethylethanamine Hydrochloride is an impurity of Diphenhydramine (D486900), is an H1-histamine receptor antagonist. Diphenhydramine is categorized as an antihistaminic; sedative, hypnotic.
References Gruhzit, O.M., et al.: J. Pharmacol. Exp. Ther., 89, 227 (1947), Holcomb, I.J., et al.: Anal. Profiles Drug Subs., 3, 173 (1974), Scavone, J.M., et al.: J. Clin. Pharmacol., 38, 603 (1998),

• Brand: TRC

Chemical properties

• Molecular weight: 305.84
• Formula: C₁₈H₂₃NO·ClH
• Color/Form: Neat
• InChI: InChI=1S/C18H23NO.ClH/c1-15-9-11-17(12-10-15)18(20-14-13-19(2)3)16-7-5-4-6-8-16;/h4-12,18H,13-14H2,1-3H3;1H
• SMILES: Cc1nc2n(c(=O)c1CC[N+]1(CCc3c(C)nc4n(c3=O)CCCC4)CCC(c3noc4cc(F)ccc34)CC1)CCCC2.[I-]