Methylphenidate Hydrochloride

CAS: 298-59-9

Ref. TR-M325880

Product Information

• Name: Methylphenidate Hydrochloride
• Synonyms: 2-Piperidineacetic acid, a-phenyl-, methyl ester, hydrochloride (1:1), 2-Piperidineacetic acid, a-phenyl-, methyl ester, hydrochloride (6CI,8CI,9CI), Centedrin, Centedrine, Concerta, Medikinet, Meridil, Metadate CD, Methyl a-phenyl-2-piperidineacetate hydrochloride, NSC 169868, Ritalin, Ritalin Hydrochloride, Ritalin SR, Methyl 2-phenyl-2-piperidineacetate hydrochloride, 2-Piperidineacetic acid, α-phenyl-, methyl ester, hydrochloride, 2-Piperidineacetic acid, α-phenyl-, methyl ester, hydrochloride (1:1), Methyl Phenyl(Piperidin-2-Yl)Acetate Hydrochloride (1:1), Methyl α-phenyl-2-piperidineacetate hydrochloride, Methylphenidate HCl, Quillivant XR, Ritalin LA, methyl (2R)-phenyl[(2S)-piperidin-2-yl]ethanoate

Description

Applications Controlled substance (stimulant). CNS stimulant. Four isomers of Methylphenidate are known to exist. One pair of threo isomers and one pair of erythro are distinguished, from which only d-threo-Methylphenidate exhibits the pharmacologically usually desired effects. This compound is a 4:1 mixture of rac-erythro (M325670) and rac-threo (M325671).
References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961), Padmanabhan, G.R., Anal. Profiles Drug Subs., 10, 473 (1981), Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993),

• Brand: TRC

Chemical properties

• Molecular weight: 269.77
• Formula: C₁₄H₁₉NO₂·ClH
• Color/Form: White
• InChI: InChI=1S/C14H19NO2.ClH/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12, 1H, /h2-4,7-8,12-13,15H,5-6,9-10H2,1H3
• InChI key: InChIKey=JUMYIBMBTDDLNG-UHFFFAOYSA-N
• SMILES: COC(=O)C(c1ccccc1)C1CCCCN1.Cl