Methylphenidate Hydrochloride

CAS: 298-59-9

Ref. TR-M325880

Product Information

• Name: Methylphenidate Hydrochloride
• Synonyms: 2-Piperidineacetic acid, α-phenyl-, methyl ester, hydrochloride (1:1), 2-Piperidineacetic acid, α-phenyl-, methyl ester, hydrochloride (6CI,8CI,9CI), Centedrin, Centedrine, Concerta, Medikinet, Meridil, Metadate CD, Methyl α-phenyl-2-piperidineacetate hydrochloride, NSC 169868, Ritalin, Ritalin Hydrochloride, Ritalin SR, Methyl 2-phenyl-2-piperidineacetate hydrochloride, 2-Piperidineacetic acid, α-phenyl-, methyl ester, hydrochloride, 2-Piperidineacetic acid, α-phenyl-, methyl ester, hydrochloride (1:1), Methyl Phenyl(Piperidin-2-Yl)Acetate Hydrochloride (1:1), Methylphenidate HCl, Quillivant XR, Ritalin LA, methyl (2R)-phenyl[(2S)-piperidin-2-yl]ethanoate
• CAS: 298-59-9

Description

Applications Controlled substance (stimulant). CNS stimulant. Four isomers of Methylphenidate are known to exist. One pair of threo isomers and one pair of erythro are distinguished, from which only d-threo-Methylphenidate exhibits the pharmacologically usually desired effects. This compound is a 4:1 mixture of rac-erythro (M325670) and rac-threo (M325671).
References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961), Padmanabhan, G.R., Anal. Profiles Drug Subs., 10, 473 (1981), Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993),

• Brand: TRC

Chemical properties

• Molecular weight: 269.77
• Formula: C₁₄H₁₉NO₂•HCl
• Color/Form: White
• InChI: InChI=1S/C14H19NO2.ClH/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12, /h2-4,7-8,12-13,15H,5-6,9-10H2,1H3, 1H
• InChI key: InChIKey=JUMYIBMBTDDLNG-UHFFFAOYSA-N
• SMILES: COC(=O)C(c1ccccc1)C1CCCCN1.Cl