(11,12,12,6α-Methyl-D6)-Prednisolone

CAS: 83-43-2

Ref. TR-M327232

Product Information

• Name: (11,12,12,6α-Methyl-D6)-Prednisolone
• Synonyms: (6α,11β)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione-d6, Medrone-d6, Medrol-d6, Medrate-d6
• Brand: TRC
• Description: Applications (11,12,12,6α-Methyl-D6)-Prednisolone is the labeled analogue of 6α-Methyl Prednisolone (M325934), a glucocorticoid which displays anti-inflamatory and antioxidant properties and attenuates apoptosis in oligodendrocytes after injury. 6α-Methyl Prednisolone is neuroprotective.References Hall, E.D., et al.: J. Neurosurg., 76, 13 (1992); Hommes, O.R., et al.: Mult. Scler., 1, 327 (1996); Bracken, M.B., et al.: J. Neurosurg., 89, 699 (1998); Dammers, J.W.H.H., et al.: Brit. Med. J., 319, 884 (1999)

Chemical properties

• Molecular weight: 380.508
• Formula: C₂₂D₆H₂₄O₅
• Color/Form: Neat
• InChI: InChI=1S/C22H30O5/c1-12-8-14-15-5-7-22(27,18(26)11-23)21(15,3)10-17(25)19(14)20(2)6-4-13(24)9-16(12)20/h4,6,9,12,14-15,17,19,23,25,27H,5,7-8,10-11H2,1-3H3/t12-,14-,15-,17-,19+,20-,21-,22-/m0/s1/i1D3,10D2,17D
• InChI key: InChIKey=VHRSUDSXCMQTMA-WUDTYJIMSA-N
• SMILES: [2H]C([2H])([2H])[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C([2H])([2H])[C@]([2H])(O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12