Product Information
Name:6-Methylthioguanine
Synonyms:
- 9H-Purin-2-amine
- 6-(methylthio)-
- 1H-Purin-2-amine
- 6-(methylthio)- (9CI)
- Purine
- 2-amino-6-(methylthio)- (6CI,7CI,8CI)
- 6-(Methylthio)-9H-purin-2-amine
- 2-Amino-6-methylmercaptopurine
- 2-Amino-6-methylthiopurine
- NSC 29420
- S-Methyl-6-thioguanine
- See more synonyms
Brand:TRC
Description:Applications A metabolite of 2’-Deoxy-6-thio Guanosine (D281650) and 6-Thioguanine. An effective immunosuppressant and anticancer agent, however chronic exposure can be mutagenic in human cells as long-term use of thiopurines was found to be associated with a significantly increased risk of various types of cancer.References Loo, T.L. et al.: Cancer Chemother. Pharmacol., 6, 131 (1981); Yuan, B. et al.: ACS Chem. Biol., 5, 1021 (2010); Kroplin, T. et al.: Adv. Exp. Med. Biol., 431, 741 (1998);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:181.22
Formula:C6H7N5S
Color/Form:Neat
InChI:InChI=1S/C6H7N5S/c1-12-5-3-4(9-2-8-3)10-6(7)11-5/h2H,1H3,(H3,7,8,9,10,11)
InChI key:InChIKey=YEGKYFQLKYGHAR-UHFFFAOYSA-N
SMILES:CSc1nc(=N)[nH]c2[nH]cnc12
Technical inquiry about: 6-Methylthioguanine
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