(aR)-a-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine (>90%)

CAS: 1428185-71-0

Ref. TR-M331080

Product Information

• Name: (aR)-a-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine (>90%)
• Synonyms: 1-Naphthalenemethanamine, α-methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-, (αR)-, (αR)-α-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine, (R)-N-[1-(Naphthalen-1-yl)ethyl]-3-[4-(trifluoromethyl)phenyl]propan-1-amine
• Brand: TRC
• Description: Applications (αR)-α-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine, is an impurity of Cinacalcet (C441800), which is a drug that acts as a calcimimetic, and is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels).References Franceschini N., et al.: Expert Opin. Invest. Drugs, 12, 1413 (2003), Block, G.A., et al.: N. Engl. J. Med. 350, 1516 (2004),

Chemical properties

• Molecular weight: 357.41
• Formula: C₂₂H₂₂F₃N
• Purity: >90%
• Color/Form: Neat
• InChI: InChI=1S/C22H22F3N/c1-16(20-10-4-8-18-7-2-3-9-21(18)20)26-15-5-6-17-11-13-19(14-12-17)22(23,24)25/h2-4,7-14,16,26H,5-6,15H2,1H3/t16-/m1/s1
• InChI key: InChIKey=MATILKQDYNBOJK-MRXNPFEDSA-N
• SMILES: C[C@@H](NCCCc1ccc(C(F)(F)F)cc1)c1cccc2ccccc12