(3R,4R)-4-Methyl-3-(methylamino)-β-oxo-1-piperidinepropanenitrile

CAS: 1629858-78-1

Ref. TR-M332845

Product Information

• Name: (3R,4R)-4-Methyl-3-(methylamino)-β-oxo-1-piperidinepropanenitrile
• Synonyms: 3-[(3R,4R)-4-methyl-3-(methylamino)piperidin-1-yl]-3-oxopropanenitrile
• Brand: TRC

Description

Applications (3R,4R)-4-Methyl-3-(methylamino)-β-oxo-1-piperidinepropanenitrile is an intermediate used in the preparation of Tofacitinib.
References Wang, H., et al.: From Faming Zhuanli Shenqing (2014), CN 104059016 A 20140924

Chemical properties

• Molecular weight: 195.262
• Formula: C₁₀H₁₇N₃O
• Color/Form: Neat
• InChI: InChI=1S/C10H17N3O/c1-8-4-6-13(7-9(8)12-2)10(14)3-5-11/h8-9,12H,3-4,6-7H2,1-2H3/t8-,9+/m1/s1
• SMILES: CN[C@H]1CN(C(=O)CC#N)CC[C@H]1C