Mexrenone

CAS: 41020-65-9

Ref. TR-M340840

Product Information

• Name: Mexrenone
• Synonyms: Pregn-4-ene-7,21-dicarboxylic acid, 17-hydroxy-3-oxo-, ?-lactone, 7-methyl ester, (7a,17a)-, Pregn-4-ene-7,21-dicarboxylic acid, 17-hydroxy-3-oxo-, ?-lactone, methyl ester, (7a,17a)- (9CI), Spiro[17H-cyclopenta[a]phenanthrene-17,2'(5'H)-furan], pregn-4-ene-7,21-dicarboxylic acid deriv., 17-Hydroxy-3-oxo-17a-pregn-4-ene-7a,21-dicarboxylic acid methyl ester ?-lactone, 17-Hydroxy-7a-(methoxycarbonyl)-3-oxo-17a-pregn-4-ene-21-carboxylic acid lactone, 7a-(Methoxycarbonyl)canrenone, SC 25152, ZK 32055, 7a-(Methoxycarbonyl)-3-oxo-17a-pregn-4-ene-21,17-carbolactone

Description

Applications Mexrenone is an impurity of eplerenon (E588775). Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),

• Brand: TRC

Chemical properties

• Molecular weight: 400.5079
• Formula: C₂₄H₃₂O₅
• Color/Form: Off-White
• InChI: InChI=1S/C24H32O5/c1-22-8-4-15(25)12-14(22)13-16(21(27)28-3)20-17(22)5-9-23(2)18(20)6-10-24(23)11-7-19(26)29-24/h12,16-18,20H,4-11,13H2,1-3H3/t16-,17+,18+,20-,22+,23+,24-/m1/s1