MG-101 (ALLN)

CAS: 110044-82-1

Ref. TR-M340950

Product Information

• Name: MG-101 (ALLN)
• Synonyms: (S)-N-Acetyl-L-leucyl-N-(1-formylpentyl)-L-leucinamide, ALLN, ALLnL, CI-1 (peptide), Calp I, Calpain inhibitor I, MG 101, (S)-N-Acetyl-L-leucinyl-L-leucinyl-L-norleucinal, <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-(1-formylpentyl)-, (S)-, <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-[(1S)-1-formylpentyl]-, ALLNal, Mg 101, N-Ac-Leu-Leu-Norleucinal, N-Acetyl-<span class="text-smallcaps">L</smallcap>-leucinyl-<smallcap>L</smallcap>-leucinyl-<smallcap>L</span>-norleucinal, N-Acetyl-<span class="text-smallcaps">L</smallcap>-leucyl-N-[(1S)-1-formylpentyl]-<smallcap>L</span>-leucinamide, N-Acetyl-L-Leucyl-L-Leucyl-L-Norleucinal, N-Acetyl-Leu-Leu-Nle-Cho, N-Acetyl-Leu-Leu-Norleucinal, N-acetyl-L-leucyl-N-[(2S)-1-oxohexan-2-yl]-L-leucinamide, N-acetyl-L-leucyl-N-[(2S)-1-oxohexan-2-yl]leucinamide, N-acetylleucyl-N-(1-oxohexan-2-yl)leucinamide
• CAS: 110044-82-1

Description

Applications MG-101 (ALLN) is a potent inhibitor of cysteine proteases including caplains and cathespins. Used in the treatment of genotoxic agents or replication stress of cells. Neuroprotective product.
References Wang, H. et al.: Biochem., 54, 5781 (2015); Fukunaga, Y. et al.: Neurosci. Res., 101, 6 (2014);

• Brand: TRC

Chemical properties

• Molecular weight: 383.53
• Formula: C₂₀H₃₇N₃O₄
• Color/Form: White to Off-White Solid
• InChI: InChI=1S/C18H24O4/c19-13(7-6-12-4-2-1-3-5-12)8-9-14-15-10-18(21)22-17(15)11-16(14)20/h1-5,13-17,19-20H,6-11H2/t13-,14+,15+,16+,17-/m0/s1
• InChI key: InChIKey=CQVHXVLSHMRWEC-UTSKFRMZSA-N
• SMILES: O=C1C[C@H]2[C@H](C[C@@H](O)[C@@H]2CC[C@@H](O)CCc2ccccc2)O1