Miltirone

CAS: 27210-57-7

Ref. TR-M344500

Product Information

• Name: Miltirone
• Synonyms: 8,8-dimethyl-2-propan-2-yl-6,7-dihydro-5H-phenanthrene-3,4-dione, 3,4-Phenanthrenedione, 5,6,7,8-tetrahydro-2-isopropyl-8,8-dimethyl-, 3,4-Phenanthrenedione, 5,6,7,8-tetrahydro-8,8-dimethyl-2-(1-methylethyl)-, 5,6,7,8-Tetrahydro-8,8-dimethyl-2-(1-methylethyl)-3,4-phenanthrenedione, 8,8-Dimethyl-2-(Propan-2-Yl)-5,6,7,8-Tetrahydrophenanthrene-3,4-Dione, Miltiron, NSC 639662, Rosmariquinone

Description

Applications An active component in Salvia miltiorrhiza that has been shown to inhibit the increase in the abundance of the mRNA for the α4 subunit of the GABAA receptor induced by ethanol withdrawal in cultured hippocampal neurons. A potential phytotherapeutic agent in the treatment of alcohol dependence.
References Mostallino, M. et al.: Eur. J. Pharmacol., 494, 83 (2004); Abenavoli, L. et al.: Rec. Prog. Med. Plants, 29, 19 (2010); Colombo, G. et al.: Alcohol. Clin. Exp. Res., 30, 754 (2006);

• Brand: TRC

Chemical properties

• Molecular weight: 282.38
• Formula: C₁₉H₂₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C19H22O2/c1-11(2)14-10-12-7-8-15-13(6-5-9-19(15,3)4)16(12)18(21)17(14)20/h7-8,10-11H,5-6,9H2,1-4H3
• InChI key: InChIKey=FEFAIBOZOKSLJR-UHFFFAOYSA-N
• SMILES: CC(C)C1=Cc2ccc3c(c2C(=O)C1=O)CCCC3(C)C