Product Information
Name:Misonidazole
Controlled Product
Synonyms:
- α-(Methoxymethyl)-2-nitro-1H-imidazole-1-ethanol
- α-(Methoxymethyl)-2-nitroimidazole-1-ethanol
- 1-(2-Hydroxy-3-methoxypropyl)-2-nitroimidazole
- 1-(2-Nitro-1-imidazolyl)-3-methoxy-2-propanol
- 2-Nitro-1H-imidazole-1-(3-methoxy-2-propanol)
- NSC 261037
- Racemic Misonidazole
- Ro 7-0582
- SR 1354
- SRI 1354
Brand:TRC
Description:Applications Misonidazole can be used as a potential hypoxic cancer cell radiosensitizer and DNA binding and nicking agent. The metabolites of misonidazole can themselves be cytotoxic or they can increase the chemosensitivity and radiosensitivity of the target cellsReferences Bonnet, M., et al.: Bioorg. Med. Chem., 22, 2123 (2014); Edwards, D.I.: Comprehensive Med. Chem., 2, 725 (1990); Murata, R., et al.: Radiother. Oncol., 87, 331 (2008); Brown, J.M. The mechanisms of cytotoxicity and chemosensitization by misonidazole and other nitroimidazoles. Int.J.Radiat.Oncol.Biol.Phys. 8(3-4), 675-682 (1982).
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:201.180
Formula:C7H11N3O4
Color/Form:Yellow Solid
InChI:InChI=1S/C7H11N3O4/c1-14-5-6(11)4-9-3-2-8-7(9)10(12)13/h2-3,6,11H,4-5H2,1H3
SMILES:COCC(O)Cn1ccnc1[N+](=O)[O-]
Technical inquiry about: Misonidazole
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