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N-​(4-​Methoxyphenyl)​-​4-​oxo-L-alloisoleucine Ethyl Ester

CAS:

Ref. TR-M409115

N-​(4-​Methoxyphenyl)​-​4-​oxo-L-alloisoleucine Ethyl Ester
TRC

    Product Information

    Name:N-​(4-​Methoxyphenyl)​-​4-​oxo-L-alloisoleucine Ethyl Ester
    Controlled Product
    Synonyms:
    • (2S,3S)-Ethyl 2-((4-methoxyphenyl)amino)-3-methyl-4-oxopentanoate
    Brand:TRC
    Description:

    Applications N-​(4-​Methoxyphenyl)​-​4-​oxo-L-alloisoleucine Ethyl Ester is an intermediate in the synthesis of (4S)-4-Hydroxy-L-isoleucine (H943570), which is 4S isomer of 4-Hydroxyisoleucine, which is used as a treatment for type II diabetes.
    References Martinez-Force, E., et al.: Biotechnol. Tech., 5, 209 (1991); Sauvaire, Y., et al.: Diabetes, 47, 206 (1998), Narender, T., et al.: Bioorg. Med. Chem. Lett., 2006, 16, 293 (2006);

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    Chemical properties

    Molecular weight:279.332
    Formula:C15H21NO4
    Color/Form:Neat
    InChI:InChI=1S/C15H21NO4/c1-5-20-15(18)14(10(2)11(3)17)16-12-6-8-13(19-4)9-7-12/h6-10,14,16H,5H2,1-4H3/t10-,14+/m1/s1
    InChI key:InChIKey=GBGNRFZGTLOKJF-YGRLFVJLSA-N
    SMILES:CCOC(=O)[C@@H](Nc1ccc(OC)cc1)[C@H](C)C(C)=O

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