Estimated delivery in United States, on Thursday 9 Jan 2025
Product Information
Name:
ML-213
Controlled Product
Synonyms:
- (1R,3R,4S)-N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-3-carboxamide
Description:
Applications ML-213 is a selective KV7.2 (KCNQ2) and KV7.4 (KCNQ4) channel opener (EC50 values are 230 and 510 nM for KV7.2 and KV7.4 respectively). ML-213 displays >80-fold selectivity against KV7.1, KV7.3 and KV7.5 in a thallium-based fluorescence assay.
References Rundfeldt, C., et al.: Eur. J. Pharmacol., 336, 243 (1997); Singh, N., et al.: Brain, 126, 2726 (2003); Munro, G., et al.: J. Med. Chem., 50, 2576 (2007); Qi, J., et al.: Eur. J. Med. Chem., 46, 934 (2011);
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
257.371
Formula:
C17H23NO
Color/Form:
Neat
InChI:
InChI=1S/C17H23NO/c1-10-6-11(2)16(12(3)7-10)18-17(19)15-9-13-4-5-14(15)8-13/h6-7,13-15H,4-5,8-9H2,1-3H3,(H,18,19)/t13-,14+,15-/m1/s1
InChI key:
InChIKey=SIQGKPGBLYKQBB-UHFFFAOYSA-N
SMILES:
Cc1cc(C)c(NC(=O)C2CC3CCC2C3)c(C)c1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-M425300 ML-213
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