cis-Montelukast

CAS: 774538-96-4

Ref. TR-M568005

Product Information

• Name: cis-Montelukast
• Synonyms: 1-[[[(1R)-1-[3-[(1Z)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic Acid, Montelukast Impurity G, Montelukast EP Impurity G, Montelukast USP Related Compound G, Montelukast cis Isomer, 1-[[[(1R)-1-[3-[(1Z)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid

Description

Impurity Montelukast EP Impurity G; Montelukast USP Related Compound G; Montelukast Cis-Isomer
Stability Light Sensitive
Applications cis-Montelukast (Montelukast EP Impurity G; Montelukast USP Related Compound G; Montelukast cis Isomer) is a cis geometric isomer of Montelukast. An impurity of Montelukast.
References Schoors, D., et al.: Br. J. Clin. Pharmacol., 40, 277 (1995), Amin, R., et al.: J. Pharm. Biomed. Anal., 13, 155 (1995), Reiss, T., et al.: J. Allergy Clin. Immunol., 98, 528 (1996),

• Brand: TRC

Chemical properties

• Molecular weight: 586.18
• Formula: C₃₅H₃₆ClNO₃S
• Color/Form: Light Yellow
• InChI: InChI=1S/C35H36ClNO3S/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39)/b15-10-/t32-/m1/s1
• InChI key: InChIKey=UCHDWCPVSPXUMX-LNMNGANESA-N
• SMILES: CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(=O)O)CC1)c1cccc(/C=C\c2ccc3ccc(Cl)cc3n2)c1