Moricizine

CAS: 31883-05-3

Ref. TR-M635025

Product Information

• Name: Moricizine
• Synonyms: N-[10-[3-(4-morpholinyl)-1-oxopropyl]-10H-phenothiazin-2-yl]Carbamic Acid Ethyl Ester, 10-(3-Morpholinopropionyl)phenothiazine-2-carbamic Acid Ethyl Ester, Ethyl 10-(beta-N-Morpholinylpropionyl)phenothiazine-2-carbamate, Ethyl 10-(beta-Morpholinopropionyl)phenothiazine-2-carbamate, G 214, Moracizine, Carbamic acid, N-[10-[3-(4-morpholinyl)-1-oxopropyl]-10H-phenothiazin-2-yl]-, ethyl ester, Ethyl 10-(β-N-morpholinylpropionyl)phenothiazine-2-carbamate, Ethyl 10-(β-morpholinopropionyl)phenothiazine-2-carbamate, Moracizin, Moracizina, Phenothiazine-2-carbamic acid, 10-(3-morpholinopropionyl)-, ethyl ester, [10-(3-Morpholin-4-yl-propionyl)-10H-phenothiazin-2-yl]-carbamic acid ethyl ester, Carbamic acid, [10-[3-(4-morpholinyl)-1-oxopropyl]-10H-phenothiazin-2-yl]-, ethyl ester

Description

Applications Moricizine, is Phenothiazine (P318040) derivative, which It was used as an Antiarrhythmic agent. It is also shown that moracizine is effective in suppressing premature ventricular contractions, couplets, and nonsustained ventricular tachycardia.
References Ahmmed, G. U., et al.: Vas. Pharm., 38, 131 (2002), Bansode, T., et al.: Eur. J. Med. Chem., 44, 5094 (2009), Baell, J., et al.: J. Med. Chem., 53, 2719 (2010), Howard, P., et al.: Environ. Sci. Technol., 44, 2277 (2010), Koren, J., et al.: J. Biol. Chem., 285, 2498 (2010), Amobi, N., et al.: Eur. J. Pharmacol., 627, 285 (2010),

• Brand: TRC

Chemical properties

• Molecular weight: 427.52
• Formula: C₂₂H₂₅N₃O₄S
• Color/Form: Neat
• InChI: InChI=1S/C22H25N3O4S/c1-2-29-22(27)23-16-7-8-20-18(15-16)25(17-5-3-4-6-19(17)30-20)21(26)9-10-24-11-13-28-14-12-24/h3-8,15H,2,9-14H2,1H3,(H,23,27)
• InChI key: InChIKey=FUBVWMNBEHXPSU-UHFFFAOYSA-N
• SMILES: CCOC(=O)Nc1ccc2c(c1)N(C(=O)CCN1CCOCC1)c1ccccc1S2