(E)-1-(4-(4-(2-Methylbut-2-en-1-yl)piperazin-1-yl)phenyl)ethanone

CAS: 938071-77-3

Ref. TR-M725994

Product Information

• Name: (E)-1-(4-(4-(2-Methylbut-2-en-1-yl)piperazin-1-yl)phenyl)ethanone
• Synonyms: 1-[4-[4-[(E)-2-methylbut-2-enyl]piperazin-1-yl]phenyl]ethanone
• Brand: TRC
• Description: Applications (E)-1-(4-(4-(2-Methylbut-2-en-1-yl)piperazin-1-yl)phenyl)ethanone is an intermediate in the synthesis of (E)-1-(4-(4-(2-Methylbut-2-en-1-yl)piperazin-1-yl)phenyl)ethanone Hydrochloride (M725995), which is a piperazinyl phenylethanone compound that acts as an inhibitor of traffic between the trans-Golgi network (TGN) and endosomes that depends on the clathrin adaptor complex AP-1. Additionally, Membrane Traffic Inhibitor, A5 has been shown to have little effect against other trafficking pathways involving endosomes and TGN.References Duncan, M. C., et al.: Proc. Natl. Acad. Sci. U S A, 104, 6235 (2007)

Chemical properties

• Molecular weight: 272.385
• Formula: C₁₇H₂₄N₂O
• Color/Form: Neat
• InChI: InChI=1S/C17H24N2O/c1-4-14(2)13-18-9-11-19(12-10-18)17-7-5-16(6-8-17)15(3)20/h4-8H,9-13H2,1-3H3/b14-4+
• InChI key: InChIKey=SBANNMOEYYSRDA-LNKIKWGQSA-N
• SMILES: C/C=C(\C)CN1CCN(c2ccc(C(C)=O)cc2)CC1