Product Information
Name:MPEP Hydrochloride
Controlled Product
Synonyms:
- 2-Methyl-6-(phenylethynyl)pyridine Hydrochloride
Brand:TRC
Description:
Stability Light Sensitive
Applications MPEP is a potent and highly selective non-competitive mGlu5a receptor antagonist (1,2). It is also a positive allosteric modulator at mGlu4 receptors.MPEP exhibits anxiolytic and antidepressant properties that may be applicable for treating schizophrenia (3).
References (1) Latif-Hemandez, A., et al.: Front Cell Neurosci. 10, 252 (2016)(2) Hikichi, H. et al.: Eur. J. Pharmacol., 639, 99 (2010)(3) Inta, I., et al.: Pharmacopsychiatry. 49, 142 (2016)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:229.7
Formula:C14H12ClN
Color/Form:Neat
InChI:InChI=1S/C14H11N.ClH/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13;/h2-9H,1H3;1H
InChI key:InChIKey=KVHKWAZUPPBMLL-UHFFFAOYSA-N
SMILES:OC(c1ccc(-c2ccc(CN3CCN(Cc4ccncc4)CC3)cc2)c(F)c1)(C(F)(F)F)C(F)(F)F
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