(2R,3S)-rel-Nadolol-N-[(2R,3S)-rel-Nadolol-de(N-tert-butyl)]

CAS: 67247-26-1

Ref. TR-N201065

Product Information

• Name: (2R,3S)-rel-Nadolol-N-[(2R,3S)-rel-Nadolol-de(N-tert-butyl)]
• Synonyms: Nadolol Impurity D, (2S,3R)-rel-5,5'-[[(1,1-Dimethylethyl)imino]bis[(2-hydroxy-3,1-propanediyl)oxy]]bis[1,2,3,4-tetrahydro-2,3-naphthalenediol, (2S,3R)-rel-5-(3-(tert-Butyl(3-(((6R,7S)-6,7-dihydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)oxy)-2-hydroxypropyl)amino)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol
• Brand: TRC
• Description: Applications (2R,3S)-rel-Nadolol-N-[(2R,3S)-rel-Nadolol-de(N-tert-butyl)]is an impurity of Nadolol (N201050), a β-Adrenergic blocker. Antihypertensive; antianginal.References Dreyfuss, J., et al.: J. Clin. Pharmacol., 17, 300 (1977); Sibley, P.L., et al.: Toxicol. Appl. Pharmacol., 44, 379 (1978); Slusarek, L., et al.: Anal. Profiles Drug Subs., 9, 455 (1980)

Chemical properties

• Molecular weight: 545.66
• Formula: C₃₀H₄₃NO₈
• Color/Form: White Solid
• InChI: InChI=1S/C30H43NO8/c1-30(2,3)31(14-20(32)16-38-28-8-4-6-18-10-24(34)26(36)12-22(18)28)15-21(33)17-39-29-9-5-7-19-11-25(35)27(37)13-23(19)29/h4-9,20-21,24-27,32-37H,10-17H2,1-3H3/t20?,21?,24-,25+,26+,27-
• InChI key: InChIKey=QTDWBPBQCMSEPA-NZBQUHSCSA-N
• SMILES: CC(C)(C)N(CC(O)COc1cccc2c1C[C@H](O)[C@H](O)C2)CC(O)COc1cccc2c1C[C@@H](O)[C@@H](O)C2