Nafoxidine Hydrochloride

CAS: 1847-63-8

Ref. TR-N212800

Product Information

• Name: Nafoxidine Hydrochloride
• Synonyms: 1-[2-[4-(3,4-dihydro-6-methoxy-2-phenyl-1-naphthalenyl)phenoxy]ethyl]-, hydrochloride (1:1)Pyrrolidine, 1-[2-[4-(3,4-dihydro-6-methoxy-2-phenyl-1-naphthalenyl)phenoxy]ethyl]-, hydrochloride (9CI), Pyrrolidine, 1-[2-[p-(3,4-dihydro-6-methoxy-2-phenyl-1-naphthyl)phenoxy]ethyl]-, hydrochloride (7CI,8CI), 1-[2-[p-(3,4-Dihydro-6-methoxy-2-phenyl-1-naphthyl)phenoxy]ethyl]pyrrolidine hydrochloride, 11100A, NSC 70735, U 11100, U 11100A, 1-(2-(p-(3,4-Dihydro-6-methoxy-2-phenyl-1-naphthyl)phenoxy)ethyl)pyrrolidine hydrochloride, 1-(2-(p-(6-Methoxy-2-phenyl-3,4-dihydro-1-naphthyl)phenoxy)ethyl)pyrrolidine hydrochloride, 1-{2-[4-(6-Methoxy-2-Phenyl-3,4-Dihydronaphthalen-1-Yl)Phenoxy]Ethyl}Pyrrolidine, Ccris 3620, Nafoxidine HCl, Nafoxidine hydrochloride [USAN:INN], Pyrrolidine 1-(2-(4-(3,4-dihydro-6-methoxy-2-phenyl-1-naphthalenyl)phenoxy)ethyl)-, hydrochloride, Pyrrolidine, 1-(2-(p-(3,4-dihydro-6-methoxy-2-phenyl-1-naphthyl)phenoxy)ethyl)-, hydrochloride, Pyrrolidine, 1-[2-[4-(3,4-dihydro-6-methoxy-2-phenyl-1-naphthalenyl)phenoxy]ethyl]-, hydrochloride (1:1), Unii-Su8Wbd61G1

Description

Applications Nafoxidine is a non-steroidal antiestrogenic drug that is structurally related to Tamoxifen (T006000). Nafoxidine is a potent estrogen receptor antagonist that exhibits anti-proliferative properties.
References Rich, R.L. et al.: Proc. Natl. Acad. Sci. USA, 99, 8562 (2002); Maertens, C. et al.: Br. J. Pharmacol., 132, 135 (2001);

• Brand: TRC

Chemical properties

• Molecular weight: 462.02
• Formula: C₂₉H₃₁NO₂·ClH
• Color/Form: Neat
• InChI: InChI=1S/C29H31NO2.ClH/c1-31-26-14-16-28-24(21-26)11-15-27(22-7-3-2-4-8-22)29(28)23-9-12-25(13-10-23)32-20-19-30-17-5-6-18-30, /h2-4,7-10,12-14,16,21H,5-6,11,15,17-20H2,1H3, 1H
• InChI key: InChIKey=HJOOGTROABIIIU-UHFFFAOYSA-N
• SMILES: COc1ccc2c(c1)CCC(c1ccccc1)=C2c1ccc(OCCN2CCCC2)cc1.Cl