Naloxone Hydrochloride

CAS: 357-08-4

Ref. TR-N285000

Product Information

• Name: Naloxone Hydrochloride
• Synonyms: Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propen-1-yl)-, hydrochloride (1:1), (5a)-, Morphinan-6-one, 17-allyl-4,5a-epoxy-3,14-dihydroxy-, hydrochloride (8CI), Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, hydrochloride, (5a)- (9CI), Normorphinone, N-allyl-7,8-dihydro-14-hydroxy-, hydrochloride (7CI), (-)-N-Allyl-14-hydroxynordihydromorphinone hydrochloride, EN 1530, EN 15304, N-Allyldihydro-14-hydroxynormorphinone hydrochloride, NIH 7890, Nalone, Nalonee, Narcan, Narcanti, l-Naloxone hydrochloride, (5Alpha)-3,14-Dihydroxy-17-Prop-2-En-1-Yl-4,5-Epoxymorphinan-6-One Hydrochloride, En 1530, En 15304, Morphinan-6-one, 17-allyl-4,5α-epoxy-3,14-dihydroxy-, hydrochloride, Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propen-1-yl)-, hydrochloride (1:1), (5α)-, Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, hydrochloride, (5α)-, Naloxone HCl, Narcoxone, Nih 7890, Normorphinone, N-allyl-7,8-dihydro-14-hydroxy-, hydrochloride

Description

Stability Hygroscopic
Applications Naloxone Hydrochloride is a specific opioid antagonist. Narcotic antagonist.
References Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967), McNicholas, L.F., et al.: Drugs, 27, 81 (1984), Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985), Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993)

• Brand: TRC

Chemical properties

• Molecular weight: 363.84
• Formula: C₁₉H₂₁NO₄·ClH
• Color/Form: Neat
• InChI: InChI=1S/C19H21NO4.ClH/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11, /m1./s1, /h2-4,14,17,21,23H,1,5-10H2, 1H/t14-,17+,18+,19-
• InChI key: InChIKey=RGPDIGOSVORSAK-STHHAXOLSA-N
• SMILES: C=CCN1CC[C@]23c4c5ccc(O)c4O[C@H]2C(=O)CC[C@@]3(O)[C@H]1C5.Cl