Product Information
Name:NB-851
Controlled Product
Synonyms:
- (4S)-4-[(1R)1-Hydroxy-2-[[1-[3-(1-methylethyl)phenyl]cyclopropyl]amino]ethyl]-19-methyl-11,16-dioxa-3,18-diazatricyclo[15.3.1.16,10]docosa-1(21),6,8,10(22),17,19-hexaen-2-one
- (4S)-4-[(1R)-1-Hydroxy-2-[[1-(3-isopropylphenyl)cyclopropyl]amino]ethyl]-19-methyl-11,16-dioxa-3,18-diazatricyclo[15.3.1.16,10]docosa-1(21),6,8,10(22),17,19-hexaen-2-one
Brand:TRC
Description:Applications NB-851 is a macrocyclic BACE-1 inhibitor reducing Aβ in brain after administration. Potential treatment for the prevention or maintenance of Alzheimer’s disease.References Lerchner, A. et al.: Bioorg. Med. Chem. Lett., 20, 603 (2010);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:543.7
Formula:C33H41N3O4
Color/Form:Neat
InChI:InChI=1S/C33H41N3O4/c1-22(2)25-9-7-10-27(19-25)33(12-13-33)34-21-30(37)29-18-24-8-6-11-28(17-24)39-14-4-5-15-40-31-20-26(32(38)36-29)16-23(3)35-31/h6-11,16-17,19-20,22,29-30,34,37H,4-5,12-15,18,21H2,1-3H3,(H,36,38)/t29-,30+/m0/s1
Technical inquiry about: NB-851
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