Nefazodone Hydrochloride

CAS: 82752-99-6

Ref. TR-N389100

Product Information

• Name: Nefazodone Hydrochloride
• Synonyms: 3H-1,2,4-Triazol-3-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-, hydrochloride (1:1)3H-1,2,4-Triazol-3-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-, monohydrochloride (9CI), BMY 13754, BMY 13754-1, Dutonin, MJ 13754-1, Serazone, Serzone, 1-[3-[4-(3-Chlorophenyl)piperazin-1-yl]propyl]-3-ethyl-4-(2-phenoxyethyl)-4,5-dihydro-1H-1,2,4-triazol-5-one hydrochloride, 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one hydrochloride (1:1), 3H-1,2,4-Triazol-3-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-, hydrochloride (1:1), 3H-1,2,4-Triazol-3-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-, monohydrochloride, Bmy 13754, Bmy 13754-1, Mj 13754-1

Description

Applications A selective serotonin 5-HT2 receptor antagonist. A novel antidepressant that shows no cardiac toxicity or anticholinergic activity common with tricyclic antidepressants.
References Eison, A.S., et al.: Psychopharmacol. Bull., 26, 311 (1990), Keller, M.B., et al.: N. Engl. J. Med., 342, 1462 (2000);

• Brand: TRC

Chemical properties

• Molecular weight: 506.47
• Formula: C₂₅H₃₂ClN₅O₂·ClH
• Color/Form: Neat
• InChI: /h3-6,8-11,20H,2,7,12-19H2,1H3, 1H, InChI=1S/C25H32ClN5O2.ClH/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22
• InChI key: InChIKey=DYCKFEBIOUQECE-UHFFFAOYSA-N
• SMILES: CCc1nn(CCCN2CCN(c3cccc(Cl)c3)CC2)c(=O)n1CCOc1ccccc1.Cl