β-Nicotinic Acid Mononucleotide-d4

CAS: 321-02-8

Ref. TR-N429393

Product Information

• Name: β-Nicotinic Acid Mononucleotide-d4
• Synonyms: 3-Carboxy-1-(5-O-phosphono-ß-D-ribofuranosyl)pyridinium Inner Salt-d4, 3-Carboxy-1-ß-D-ribofuranosylpyridinium Hydroxide 5'-Phosphate Inner Salt-d4, Nicotinate Mononucleotide-d4, Nicotinate Ribonucleotide-d4, Nicotinic Acid Ribonucleotide-d4, Nicotinic Acid Ribotide-d4, Nicotinic Mononucleotide-d4, ß-NaMN-d4, 1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium-3-carboxylate, 3-Carboxy-1-β-<span class="text-smallcaps">D</span>-ribofuranosylpyridinium hydroxide, 5′-phosphate, inner salt, 3-Pyridinecarboxylic acid, mononucleotide, 3-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium, 3-carboxy-1-(5-O-phosphonopentofuranosyl)pyridinium, Deamido nicotinamide ribonucleotide, Deamido-NMN, Nicotinate mononucleotide, Nicotinate ribonucleotide, Nicotinic acid ribonucleotide, Nicotinic acid ribotide, Nicotinic mononucleotide, Pyridinium, 3-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)-, inner salt, Pyridinium, 3-carboxy-1-(5-O-phosphono-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-, inner salt, Pyridinium, 3-carboxy-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, hydroxide, 5′-(dihydrogen phosphate), inner salt, cyclohexane-1,4-diylbis[N-(2-chlorobenzyl)methanamine] dihydrochloride, β-Nicotinic acid mononucleotide

Description

Stability Hygroscopic
Applications β-Nicotinic Acid Mononucleotide-d4 is the isotope labelled analog of β-Nicotinic Acid Mononucleotide (N429390); a nucleotide of nicotinic acid which is produced from quinolinic acid by quinolinate phosphoribosyltransferase via transfer of a phosphoribose group. It is an intermediate of nicotinic acid adenine dinucleotide (NaAD) which is then converted to NAD via amidation and in turn converted to NADPH.
References Petrelli, R. et al.: Curr. Med. Chem., 18, 1973 (2011); Shibata, K. et al.: J. Chrom. B Biomed. Sci. Appl., 749, 281 (2000); Evans, C. et al.: BMC Chem. Biol., 10, 2 (2010)

• Brand: TRC

Chemical properties

• Molecular weight: 339.23
• Formula: C₁₁H₁₀D₄NO₉P
• Purity: >90%
• Color/Form: Neat
• SMILES: [2H]c1c([2H])c([2H])[n+]([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)c([2H])c1C(=O)[O-]