N,N-Diethylnicotinamide (Nikethamide)

CAS: 59-26-7

Ref. TR-N460000

Product Information

• Name: N,N-Diethylnicotinamide (Nikethamide)
• Synonyms: Nikethamide, Anacardone, Astrocar, Inicardio, Kardiamid, Leptamin, Mediamid, Niamine, Nicamide, Nicetamide, Nicethamid, Nicor, Nicotinic Acid Diethyl Amide, Nikotin, N,N-diethyl-3-pyridinecarboxamide, N,N-Diethylnicotinamide, Percoral, Procardine, Pyridine-3-Carboxyldiethylamide, Pyridine-3-Carboxylic Acid Diethylamide, Reformin, Salvacord, Stellamine, Stimulin, Vasozol, Diethyl-Nicotamide, Dietilamide-Carbopiridina, Dinacoryl, Betapyrimidum, Camphozone, Cardiamid, Cardiamine, Cardamine, Citocor, Coracon, Coraethamidum, Coramine, Corazone, Cordiamin, Cordynil, Corediol, Coretone, Cormid, Cornotone, Corvitan, Corvotone, Danamine, Elitone, Hansacor, N,N-diethylpyridine-3-carboxamide, 3-(N,N-Diethylcarbamoyl)pyridine, 3-Pyridinecarboxamide, N,N-diethyl-, Anacordone, Canfodiamina, Carbamidal, Cardiamide, Cardimon, Coractiv N, Coramine (pharmaceutical), Cordiamine, Cormed, Cormotyl, Corvin, Corvitol, Diethylnicotinamide, Dynacoryl, Ecoran, Eucoran, Kordiamin, Nicetamida, Nicethamide, Ni-Cor, Nicorine, Nicotinamide, N,N-diethyl-, Nicotinic acid diethylamide, Nikardin, Niketamide, Niketamine, Nikethamid, Niketharol, Nikethyl, Nikorin, Niquetamide, Nsc 130820, Nsc 169863, Nsc 62103, Pyricardyl, Pyridine-3-carboxydiethylamide, Rehormin, Salvacard, Sancora, Solyacord, Ventramine

Description

Applications Nikethamide is an analeptic agent. It was used in the mid-twentieth century as a medical countermeasure against tranquilizer overdoses, before the advent of endotracheal intubation and positive-pressure lung expansion. It is now considered to be of no value for such purposes, and may in fact be dangerous.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bean, J., et al.: Biochem. Pharm., 35, 1011 (1986); Chakaravarti, M.: J. Pharmacol., 67, 153 (1939); Naik, S., et al.: Biochem. Pharm., 18, 2038 (1969); Martindale, The Extra Pharmacopoeia, 30th ed,, 1229

• Brand: TRC

Chemical properties

• Molecular weight: 178.23
• Formula: C₁₀H₁₄N₂O
• Color/Form: Off-White
• InChI: InChI=1S/C10H14N2O/c1-3-12(4-2)10(13)9-6-5-7-11-8-9/h5-8H,3-4H2,1-2H3
• InChI key: InChIKey=NCYVXEGFNDZQCU-UHFFFAOYSA-N
• SMILES: CCN(CC)C(=O)c1cccnc1