N,N-Diethylnicotinamide (Nikethamide)

CAS: 59-26-7

Ref. TR-N460000

Product Information

• Name: N,N-Diethylnicotinamide (Nikethamide)
• Synonyms: 3-Pyridinecarboxamide, N,N-diethyl-, Nicotinamide, N,N-diethyl- (8CI), N,N-Diethyl-3-pyridinecarboxamide, 3-(N,N-Diethylcarbamoyl)pyridine, Anacardone, Anacordone, Astrocar, Canfodiamina, Carbamidal, Cardamine, Cardiamid, Cardiamide, Cardiamine, Cardimon, Coracon, Coractiv N, Coramine, Coramine (pharmaceutical), Cordiamin, Cordiamine, Corediol, Cormed, Cormid, Cormotyl, Cornotone, Corvin, Corvitol, Corvotone, Diethylnicotinamide, Dynacoryl, Ecoran, Eucoran, Kordiamin, N,N-Diethylnicotinamide, NSC 130820, NSC 169863, NSC 62103, Ni-Cor, Niamine, Nicamide, Nicetamide, Nicethamide, Nicorine, Nicotinic acid diethylamide, Nikardin, Niketamide, Niketamine, Nikethamide, Niketharol, Nikethyl, Nikorin, Niquetamide, Percoral, Pyricardyl, Pyridine-3-carboxydiethylamide, Pyridine-3-carboxylic acid diethylamide, Reformin, Rehormin, Salvacard, Sancora, Solyacord, Stimulin
• Brand: TRC

Description

Applications Nikethamide is an analeptic agent. It was used in the mid-twentieth century as a medical countermeasure against tranquilizer overdoses, before the advent of endotracheal intubation and positive-pressure lung expansion. It is now considered to be of no value for such purposes, and may in fact be dangerous.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bean, J., et al.: Biochem. Pharm., 35, 1011 (1986); Chakaravarti, M.: J. Pharmacol., 67, 153 (1939); Naik, S., et al.: Biochem. Pharm., 18, 2038 (1969); Martindale, The Extra Pharmacopoeia, 30th ed,, 1229

Chemical properties

• Molecular weight: 178.23
• Formula: C₁₀H₁₄N₂O
• Color/Form: Neat
• InChI: InChI=1S/C10H14N2O/c1-3-12(4-2)10(13)9-6-5-7-11-8-9/h5-8H,3-4H2,1-2H3
• InChI key: InChIKey=NCYVXEGFNDZQCU-UHFFFAOYSA-N
• SMILES: CCN(CC)C(=O)c1cccnc1