Product Information
Name:Nilotinib-d3
Controlled Product
Synonyms:
- 4-Methyl-N-[3-(4-(methyl-d3)-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide
- AMN 107-d3
- Tasigna-d3
Brand:TRC
Description:Applications Labelled analog of Nilotinib (AMN1O7), which might be useful in treatment of chronic myelogenous leukemia. It is a COVID19-related research product.References Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:532.53
Formula:C282H3H19F3N7O
Color/Form:Off-White To Light Yellow
InChI:InChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37)/i2D3
InChI key:InChIKey=HHZIURLSWUIHRB-BMSJAHLVSA-N
SMILES:[2H]C([2H])([2H])c1cn(-c2cc(NC(=O)c3ccc(C)c(Nc4nccc(-c5cccnc5)n4)c3)cc(C(F)(F)F)c2)cn1
Technical inquiry about: Nilotinib-d3
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