Nimesulide

CAS: 51803-78-2

Ref. TR-N477500

Product Information

• Name: Nimesulide
• Synonyms: N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide, 2-Phenoxy-4-nitromethanesulfonanilide, 4'-Nitro-2'-phenoxymethanesulfonanilide, 4-Nitro-2-phenoxymethanesulfonanilide, Aulin, Flogovital, Mesulid, Nimed, Nimepast, Nimulid, Nisulid, Orthobid, Sulidene, Lizepat, Mesulide, Methanesulfonamide, N-(4-nitro-2-phenoxyphenyl)-, Methosulide, N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide, Nicip, Nimalox, Nimesulid, Nimesulida, Nimsulid, Nise*Gel, Nise^*Gel, Nizer, R 805, R 805 (pharmaceutical), Sulidan, Sulide

Description

Applications Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Pairet, M., et al.: Inflamm. Res., 47, S93 (1998), Fukutake, M., et al.: Carcinogenesis, 19, 1939 (1998), Okajima., E., et al.: Cancer Res., 58, 3028 (1998), Azab, A., et al.: Life Sci., 63, 323 (1998)

• Brand: TRC

Chemical properties

• Molecular weight: 308.31
• Formula: C₁₃H₁₂N₂O₅S
• Color/Form: Light Yellow Solid
• InChI: InChI=1S/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3
• SMILES: CS(=O)(=O)Nc1ccc([N+](=O)[O-])cc1Oc1ccccc1