Nimustine Hydrochloride

CAS: 55661-38-6

Ref. TR-N478253

Product Information

• Name: Nimustine Hydrochloride
• Synonyms: N'-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-(2-chloroethyl)-N-nitrosourea Monohydrochloride, 1-(4-Amino-2-methylpyrimidin-5-yl)methyl-3-(2-chloroethyl)-3-nitrosourea Hydrochloride, ACNU, NSC-D 245382, Nidran, 1-(4-Amino-2-methylpyrimidin-5-yl)methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride, 3-[(4-Amino-2-Methyl-5-Pyrimidinyl)Methyl]-1-(2-Chloroethyl)-1-Nitrosourea Hydrochloride, 3-[(4-Amino-2-Methyl-Pyrimidin-5-Yl)Methyl]-1-(2-Chloroethyl)-1-Nitroso-Urea Hydrochloride, Cs-439, Nsc-D 245382, Urea, N′-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(2-chloroethyl)-N-nitroso-, hydrochloride (1:1), Urea, N′-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(2-chloroethyl)-N-nitroso-, monohydrochloride

Description

Applications Nimustine Hydrochloride is a DNA alkylator and cross-linking agent. It is used in chemotherapy in a part of anti-cancer cocktail used to treat malignant melanoma.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Matsumoto, T. et al.: J. Eur. Acad. Dermatol. Venereol., 27, 1514 (2013);

• Brand: TRC

Chemical properties

• Molecular weight: 272.69 + (36.46)
• Formula: C₉H₁₃ClN₆O₂·(HCl)
• Color/Form: Neat
• InChI: InChI=1S/C9H13ClN6O2.ClH/c1-6-12-4-7(8(11)14-6)5-13-9(17)16(15-18)3-2-10;/h4H,2-3,5H2,1H3,(H,13,17)(H2,11,12,14);1H
• InChI key: InChIKey=KPMKNHGAPDCYLP-UHFFFAOYSA-N
• SMILES: Cc1ncc(CNC(=O)N(CCCl)N=O)c(N)n1.Cl