Product Information
Name:Niraparib
Controlled Product
Synonyms:
- 2H-Indazole-7-carboxamide
- 2-[4-(3S)-3-piperidinylphenyl]-
- 2-[4-(3S)-3-Piperidinylphenyl]-2H-indazole-7-carboxamide
- Zejula
Brand:TRC
Description:Applications Niraparib is a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.References Jones, P., et al.: J. Med. Chem., 52, 7170 (2009); Giannini, G., et al.: Bioorg. Med. Chem. Lett., 24, 462 (2014)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:320.39
Formula:C19H20N4O
Color/Form:Neat
InChI:InChI=1S/C19H20N4O/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24)/t14-/m1/s1
InChI key:InChIKey=PCHKPVIQAHNQLW-CQSZACIVSA-N
SMILES:NC(=O)c1cccc2cn(-c3ccc([C@@H]4CCCNC4)cc3)nc12
Technical inquiry about: Niraparib
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