Product Information
Name:Nitisinone
Synonyms:
- 1,3-Cyclohexanedione
- 2-[2-nitro-4-(trifluoromethyl)benzoyl]- (9CI
- ACI)
- 2-[2-Nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione (ACI)
- Nitisone
- Nityr
- NTBC
- Orfadin
- SC 0735
Brand:TRC
Description:Applications Nitisinone is a herbicidal triketone that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme involved in plastoquinone biosynthesis in plants and in tyrosine catabolism in mammals. It is used in treatment of inherited tyrosinemia type I.References Lindstedt, S., et al.: Lancet, 340, 813 (1992), Ellis, M.K., et al.: Toxicol. Appl. Pharmacol., 133, 12 (1995), Lock, E.A., et al.: J. Inherited Metab. Dis., 21, 498 (1998),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:329.23
Formula:C14H10F3NO5
Color/Form:Neat
InChI:InChI=1S/C14H10F3NO5/c15-14(16,17)7-4-5-8(9(6-7)18(22)23)13(21)12-10(19)2-1-3-11(12)20/h4-6,12H,1-3H2
SMILES:O=C1CCCC(=O)C1C(=O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]
Technical inquiry about: Nitisinone
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