Nitrofurantoin

CAS: 67-20-9

Ref. TR-N493850

Product Information

• Name: Nitrofurantoin
• Synonyms: 1-[[(5-Nitro-2-furanyl)methylene]amino]-2,4-imidazolidinedione, 1-(5-Nitro-2-furfurylidenamino)hydantoin, 1-(5-Nitro-2-furfurylideneamino)hydantoin, 1-[(5-Nitrofurfurylidene)amino]hydantoin, 5-Nitrofurantoin, Berkfurin, Chemiofuran, Cyantin, Cystit, FuaMed, Fur-ren, Furachel, Furadantin, Furadantine MC, Furadantoin, Furadoin, Furadoine, Furadonin, Furadonine, Furadontin, Furalan, Furantoin, Furantoina, Furatoin, Furina, Furobactina, Furophen T-Caps, Ituran, Macrobid, Macrodantin, N-(5-Nitro-2-furfurylidene)-1-aminohydantoin, N-(5-Nitro-2-furfurylidine)-1-aminohydantoin, N-(5-Nitrofurfurylidene)-1-aminohydantoin, NSC 2107, NSC 44150, Nifurantin, Nitoin, Novofuran, Orafuran, Parfuran, Trantoin, Urantoin, Urizept, Uro-Tablinen, Urodin, Urofurin, Urolong, Welfurin, Zoofurin, 1-(5-Nitrofurfurylideneamino)Hydantoin, 1-[(5-Nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione, 1-[[(5-Nitro-2-furyl)methylene]amino]-2,4-imidazolidinone, 1-{[(5-Nitrofuran-2-Yl)Methylidene]Amino}Imidazolidine-2,4-Dione, 2,4-Imidazolidinedione, 1-[[(5-nitro-2-furanyl)methylene]amino]-, Hydantoin, 1-[(5-nitrofurfurylidene)amino]-, Macrofuran, Nitrofurantoina, Nitrofurantoine, Nsc 2107, Nsc 44150, Uvamin

Description

Applications A nitrofuran antibiotic with low resistance potential that is rapidly metabolized by mammals. Active against both Gram-positive and Gram-negative bacteria. Nitrofurantoin is also a prooxidant that is cytotoxic due to the generation of intracellular H2O2. Antibacterial.Environmental contaminants; Food contaminants; Heat processing contaminants
References Cadwallader, D.E., et al.: Anal. Profiles Drug Subs., 5, 345 (1976), Rogers, R.G., et al.: Am. J. Obstr. Gynecol., 191, 182 (2004),

• Brand: TRC

Chemical properties

• Molecular weight: 238.16
• Formula: C₈H₆N₄O₅
• Color/Form: Yellow
• InChI: InChI=1S/C8H6N4O5/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16/h1-3H,4H2,(H,10,13,14)/b9-3+
• SMILES: O=C1CN(/N=C\c2ccc([N+](=O)[O-])o2)C(=O)N1