S-Nitroso-N-acetyl-D,L-penicillamine

CAS: 67776-06-1

Ref. TR-N522500

Product Information

• Name: S-Nitroso-N-acetyl-D,L-penicillamine
• Synonyms: Valine, N-acetyl-3-(nitrosothio)- (9CI, ACI), DL-Valine, N-acetyl-3-(nitrosothio)- (ZCI), N-Acetyl-3-(nitrosothio)valine (ACI), 2-Acetamido-3-methyl-3-(nitrosothio)butanoic acid, N-Acetyl-S-nitroso-DL-penicillamine, N-Acetyl-S-nitrosopenicillamine, S-Nitroso-N-acetyl-DL-penicillamine, S-Nitrosoacetylpenicillamine, SNAP, SNAP (amino acid), 2-Acetamido-3-methyl-3-nitrososulfanyl-butanoic acid
• Brand: TRC

Description

Applications Produced concentration-related relaxations of mouse anococcygeus, in a range similar to that already found for NO and other nitrovasodilators. A potent relaxant of non-vascular smooth muscle. Serves as an NO donor.
References Bauer & Fung: J. Pharmacol. Exp. Ther., 256, 249 (1991), Gibson, A., et al.: Brit. J. Pharm., 107, 715 (1992), Shaffer, et al.: J. Pharm. Exper. Ther., 260, 286 (1992), Jansen, A., et al.: J. Pharmacol. Exp. Ther., 261, 154 (1992), Lander, H.M. et al.: J. Immunol., 150, 1509 (1993)

Chemical properties

• Molecular weight: 220.25
• Formula: C₇H₁₂N₂O₄S
• Color/Form: Neat
• InChI: InChI=1S/C7H12N2O4S/c1-4(10)8-5(6(11)12)7(2,3)14-9-13/h5H,1-3H3,(H,8,10)(H,11,12)
• InChI key: InChIKey=ZIIQCSMRQKCOCT-UHFFFAOYSA-N
• SMILES: CC(=O)NC(C(=O)O)C(C)(C)SN=O