Product Information
- 2-(2,6-Dioxo-3-piperidinyl)-4-nitro-1H-isoindole-1,3(2H)-dione
- 2-(2,6-Dioxopiperidin-3-yl)-4-nitro-isoindole-1,3-dione
- 4-Nitro-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
- 1H-isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-nitro-
- 2-(2,6-Dioxopiperidin-3-Yl)-4-Nitroisoindoline-1,3-Dione
- Ec1-078
- Phthalimide, N-(2,6-dioxo-3-piperidyl)-3-nitro-
Applications 4-Nitrothalidomide is a compound involved in the preparation of Pomalidomide (P688200), a thalidomide derivative and potent inhibitor of TNF-α production.
References Huang, D., et al.: Syn. Comm., 46, 1343-1348 (2016); Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)
Chemical properties
Technical inquiry about: TR-N565525 4-Nitrothalidomide
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