N1-Nornicergoline

CAS: 35264-46-1

Ref. TR-N756600

Product Information

• Name: N1-Nornicergoline
• Synonyms: Ergoline-8-methanol, 10-methoxy-6-methyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)-, Ergoline-8-methanol, 10-methoxy-6-methyl-, 5-bromo-3-pyridinecarboxylate (ester), (8β)- (9CI), 1-Demethylnicergoline, N1-Demethylnicergoline, [(6aR,9R,10aS)-10a-Methoxy7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]methyl 5-bromopyridine-3-carboxylate, 1-Desmethylnicergoline
• Brand: TRC
• Description: Impurity Nicergoline EP Impurity BApplications N1-Nornicergoline is an impurity of Nicergoline (N394550). Nicergoline is a drug used for age-dependent cognitive impairment and it protects cultured neurons against β-amyloid toxicity.References Mizuno, T., et. al.: Brain Res., 1066, 78 (2005)

Chemical properties

• Molecular weight: 470.36
• Formula: C₂₃H₂₄BrN₃O₃
• Color/Form: White To Beige
• InChI: InChI=1S/C23H24BrN3O3/c1-27-12-14(13-30-22(28)16-6-17(24)11-25-9-16)8-23(29-2)18-4-3-5-19-21(18)15(10-26-19)7-20(23)27/h3-6,9-11,14,20,26H,7-8,12-13H2,1-2H3/t14-,20-,23+/m1/s1
• InChI key: InChIKey=LALVMGWGWJIGIR-ZTWLPKFNSA-N
• SMILES: CO[C@]12C[C@@H](COC(=O)c3cncc(Br)c3)CN(C)[C@@H]1Cc1c[nH]c3cccc2c13