Noscapine Hydrochloride

CAS: 912-60-7

Ref. TR-N882018

Product Information

• Name: Noscapine Hydrochloride
• Synonyms: 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride (1:1), (3S)-, 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, hydrochloride, [S-(R*,S*)]-, 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride, (3S)- (9CI), Narcotine, hydrochloride (7CI,8CI), 1,3-Dioxolo[4,5-g]isoquinoline, 1(3H)-isobenzofuranone deriv., Opianine hydrochloride, l-Narcotine hydrochloride, (5R)-5-[(1S)-4,5-dimethoxy-3-oxo-1,3-dihydro-2-benzofuran-1-yl]-4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-6-ium, (5R)-5-[(1S)-4,5-dimethoxy-3-oxo-1,3-dihydro-2-benzofuran-1-yl]-4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-6-ium chloride, 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-((5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, hydrochloride, (3S)-, 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride (1:1), (3S)-, 1(3H)Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, hydrochloride, (S-(R*,S*))-, 1,3-Dioxolo[4,5-g]isoquinoline, 1(3H)-isobenzofuranone deriv., 1-alpha-Narcotine hydrochloride, Capval, Ccris 8985, Coscopin hydrochloride, Coscotabs hydrochloride, Difmetus Kapseln, Germose Noscapine, Key-tusscapine hydrochloride, Longatin, Lyobex retard, Methoxyhydrastine hydrochloride, NSC 5366 hydrochloride, Narcompren hydrochloride, Narcosine hydrochloride, Narcotine, hydrochloride, Narcotine, hydrochloride (8CI), Narcotussin, Nectadon hydrochloride, Nipaxon, Noscapine HCl, Noscapine hydrochloride, Opian hydrochloride, Stilco, Teletux, Terbenol hydrochloride, Tucotine, Tulisan, Tusscapine, Tussicure P, Unii-Ttn62Ith9I, Vadebex hydrochloride, hydrogen chloride 6,7-dimethoxy-3-(4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-2-benzofuran-1(3H)-one (1:1:1)

Description

Applications Noscapine Hydrochloride is a bradykinin B and tubulin inhibitor. Anti-viral.
References Sammeta, S. M., et al.: Pharm. Dev. Technol., 20, 169-175 (2015)

• Brand: TRC

Chemical properties

• Molecular weight: 449.88
• Formula: C₂₂H₂₃NO₇·ClH
• Color/Form: Off White
• InChI: InChI=1S/C22H23NO7.ClH/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18, 1H/t17-,18+, /h5-6,9,17-18H,7-8,10H2,1-4H3, /m1./s1
• InChI key: InChIKey=MFLVZFXCSKVCSH-URBRKQAFSA-N
• SMILES: COc1ccc2c(c1OC)C(=O)O[C@@H]2[C@H]1c2c(cc3c(c2OC)OCO3)CCN1C.Cl